Publications internationales How effective are cognitive and behavioral treatments for obsessive?compulsive disorder? A clinical significance analysis

How effective are cognitive and behavioral treatments for obsessive?compulsive disorder? A clinical significance analysis

Peter L. Fisher and Adrian Well

Revue : Behaviour Research and Therapy

Department of Clinical Psychology, Rawnsley Building, Manchester Royal Infirmary, University of Manchester, Oxford Road, Manchester M13 9WL, UK

Received 22 June 2004; revised 15 November 2004; accepted 19 November 2004. Available online 1 April 2005.



Controlled outcome studies investigating the efficacy of psychological treatments for obsessive?compulsive disorder (OCD) have employed different methods of determining the clinical significance of treatment effects. This makes it difficult to draw conclusions regarding the absolute and relative efficacy of psychological treatments for OCD. To address this issue, standardized Jacobson methodology for defining clinically significant change was applied to recent psychological outcome trials for OCD. The proportion of asymptomatic patients following treatment was also calculated. When recovery is defined by Jacobson methodology, exposure and response prevention (ERP) appears the most effective treatment currently available (50?60% recovered). However, when the asymptomatic criterion is used as the index of outcome, ERP and cognitive therapy have low and equivalent recovery rates (approximately 25%).

Keywords: Obsessive?compulsive disorder; Clinical significance; Efficacy

Behaviour Research and Therapy - Volume 43, Issue 12 - Pages 1543-1558

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